Tuesday, Nov 4th, 2025
Main Street Summit is a premier business event that brings together 1,000+ business owners, operators, and entrepreneurs for expert-led sessions across seven industry tracks, including venture/startups, manufacturing, construction, franchising, health, faith & work, and non-profit - all happening November 4-6, 2025 in Columbia, MO. This event is relevant to the Columbia community as it positions the city as a hub for small business innovation and growth, attracting world-class speakers and industry leaders to share practical insights in intimate, small-group settings rather than traditional conference formats, while showcasing Columbia as a destination for entrepreneurial excellence in the heart of Main Street America.